Enabling proteomics-based identification of human cancer variations

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparative Proteomics Analysis of Human Colon Cancer

Nutrition has evolved from providing nutrients to nourish populations to improving health of individuals through diet. Modern nutritional research focuses on health promotion and disease prevention, on protection against toxicity and stress, and on performance improvement. The concept of developing nutritionally enhanced or functional food requires (a) the understanding of the mechanisms of pre...

متن کامل

Differential expression proteomics of human colon cancer.

The focus of this study was to use differential protein expression to investigate operative pathways in early stages of human colon cancer. Colorectal cancer represents an ideal model system to study the development and progression of human tumors, and the proteomic approach avoids overlooking posttranslational modifications not detected by microarray analyses and the limited correlation betwee...

متن کامل

Identification of Novel Biomarkers for Early Detection of Human Lung Squamous Cell Cancer by Quantitative Proteomics

1 Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha 410008, China 2 Department of General Surgery and Operative Surgery, School of Medicine, University of South China, Hengyang 421001, China 3 Department of Cardiothoracic Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, China 4 Departments of R...

متن کامل

A chemical proteomics approach for the identification of accessible antigens expressed in human kidney cancer.

A promising avenue toward the development of more selective anticancer drugs consists in the targeted delivery of bioactive molecules to the tumor environment by means of binding molecules specific to tumor-associated markers. We have used a chemical proteomics approach based on the ex vivo perfusion and biotinylation of accessible structures within surgically resected human kidneys with tumor ...

متن کامل

Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer.

Gastric cancer (GC) is the one of the most common types of cancer in Asia. To better understand the molecular mechanisms underlying GC, and to seek new markers of tumor progression, we used a proteomics strategy to analyze the protein expression patterns in matched pairs of GC tissue and normal gastric mucosa of 8 GC patients. Comparative proteomic analysis, using two-dimensional gel electropho...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: BMC Bioinformatics

سال: 2010

ISSN: 1471-2105

DOI: 10.1186/1471-2105-11-s4-p29